The protocol that will be signed on Saturday will be historic as it brings the southern Caucuses closer to stability and an end to the war between Armenia and Azerbaijan (only a ceasefire is in place). A second protocol will expand on the normalization of relations and lead to a vote for ratification in Ankara and Yerevan after which the borders will be open.
The risk, of course, is that the nationalists in both Turkey and Armenia will do everything possible to assure the protocols are not ratified. This is the chosen role of nationalist parties world-wide - a single minded effort to undermine cross-border cooperation largely based on historical affronts by the other side.
Everything must be done in the case between Armenia and Turkey to push the nationalists to the side in the name of the substantial economic and political improvements to both countries.